Cast of Novocaine: Meet the Stars

Jack Quaid leads this action-comedy as Nathan Caine, a man who can’t feel pain. See the full cast and their roles in Novocaine (2025).

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Jack Quaid plays a man with a rare condition that makes him immune to pain. He must fight against dangerous enemies to save his love.

Jack Quaid as Nathan Caine

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Amber Midthunder as Lily Harper

Lily Harper is Nate’s love interest. When she is taken, Nate goes on a risky mission to get her back, using his rare condition as an advantage.

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Other Key Cast Members

Ray Nicholson, Betty Gabriel, and Matt Walsh play important roles. Their characters add depth, humor, and tension to this action-packed thriller.

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Who Made Novocaine?

Directed by Dan Berk and Robert Olsen, Novocaine was filmed in Cape Town. The movie is backed by Paramount Pictures for a major release.

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What Makes Nate Special?

Unlike superheroes, Nate has no superpowers. His rare disorder lets him take hits without pain, making him a unique and unstoppable fighter.

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Learn More

Want more on the cast, characters, and behind-the-scenes details? Read the full article on Novocaine (2025) now!

Photo Credit: Paramount+